Meiosis Study Guide
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Overview· Stages of Meiosis
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Meiosis Diagrams·
Glossary of Terms·
QuizBefore a dividing cell enters meiosis, it undergoes a period of growth called interphase.Interphase:
· G1 phase: The period prior to the synthesis of DNA. In this phase, the cell increases in mass in preparation for cell division. Note that the G in G1 represents gap and the 1 represents first, so the G1 phase is the first gap phase.
· S phase: The period during which DNA is synthesized. In most cells, there is a narrow window of time during which DNA is synthesized. Note that the S represents synthesis.
· G2 phase: The period after DNA synthesis has occurred but prior to the start of prophase. The cell synthesizes proteins and continues to increase in size. Note that the G in G2 represents gap and the 2 represents second, so the G2 phase is the second gap phase.
· In the latter part of interphase, the cell still has nucleoli present.
· The
nucleus is bounded by a nuclear envelope and the cell's chromosomes have duplicated but are in the form of
chromatin.
· In animal cells, two pair of
centrioles formed from the replication of one pair are located outside of the nucleus.
Sexual reproduction occurs only in
eukaryotes. During the formation of
gametes, the number of
chromosomes is reduced by half, and returned to the full amount when the two
gametes fuse during
fertilization.
Ploidy
Back to TopHaploid and diploid are terms referring to the number of sets of chromosomes in a cell. Gregor Mendel determined his peas had two sets of alleles, one from each parent.
Diploid organisms are those with two (di) sets. Human beings (except for their gametes), most animals and many plants are diploid. We abbreviate diploid as 2n. Ploidy is a term referring to the number of sets of chromosomes.
Haploid organisms/cells have only one set of chromosomes, abbreviated as n. Organisms with more than two sets of chromosomes are termed polyploid. Chromosomes that carry the same genes are termed
homologous chromosomes. The
alleles on homologous chromosomes may differ, as in the case of
heterozygous individuals. Organisms (normally) receive one set of homologous chromosomes from each parent.
Meiosis is a special type of nuclear division which segregates one copy of each homologous chromosome into each new "gamete". Mitosis maintains the cell's original ploidy level (for example, one diploid 2n cell producing two diploid 2n cells; one haploid n cell producing two haploid n cells; etc.). Meiosis, on the other hand, reduces the number of sets of chromosomes by half, so that when gametic recombination (
fertilization) occurs the ploidy of the parents will be reestablished.
Most cells in the human body are produced by mitosis. These are the
somatic (or vegetative) line cells. Cells that become gametes are referred to as
germ line cells. The vast majority of cell divisions in the human body are mitotic, with meiosis being restricted to the
gonads.
Life Cycles
Back to TopLife cycles are a diagrammatic representation of the events in the organism's development and reproduction. When interpreting life cycles, pay close attention to the ploidy level of particular parts of the cycle and where in the life cycle meiosis occurs. For example, animal life cycles have a dominant diploid phase, with the gametic (haploid) phase being a relative few cells. Most of the cells in your body are diploid, germ line diploid cells will undergo meiosis to produce gametes, with fertilization closely following meiosis.
Plant life cycles have two sequential phases that are termed
alternation of generations. The
sporophyte phase is "diploid", and is that part of the life cycle in which meiosis occurs. However, many plant species are thought to arise by
polyploidy, and the use of "diploid" in the last sentence was meant to indicate that the greater number of chromosome sets occur in this phase. The
gametophyte phase is "haploid", and is the part of the life cycle in which gametes are produced (by mitosis of haploid cells). In flowering plants (
angiosperms) the multicelled visible plant (leaf, stem, etc.) is sporophyte, while pollen and ovaries contain the male and female gametophytes, respectively. Plant life cycles differ from animal ones by adding a phase (the haploid gametophyte) after meiosis and before the production of gametes.
Many protists and fungi have a haploid dominated life cycle. The dominant phase is haploid, while the diploid phase is only a few cells (often only the single celled zygote, as in Chlamydomonas ). Many protists reproduce by mitosis until their environment deteriorates, then they undergo sexual reproduction to produce a resting zygotic cyst.
Phases of Meiosis
Back to TopTwo successive nuclear divisions occur, Meiosis I (Reduction) and Meiosis II (Division). Meiosis produces 4 haploid cells. Mitosis produces 2 diploid cells. The old name for meiosis was reduction/ division. Meiosis I reduces the ploidy level from 2n to n (reduction) while Meiosis II divides the remaining set of chromosomes in a mitosis-like process (division). Most of the differences between the processes occur during Meiosis I.
The above image is from
http://www.biology.uc.edu/vgenetic/meiosis/Prophase I
Back to TopProphase I has a unique event -- the pairing (by an as yet undiscovered mechanism) of
homologous chromosomes.
Synapsis is the process of linking of the replicated homologous chromosomes. The resulting chromosome is termed a
tetrad, being composed of two
chromatids from each chromosome, forming a thick (4-strand) structure.
Crossing-over may occur at this point. During crossing-over chromatids break and may be reattached to a different homologous chromosome.
The alleles on this tetrad:
A B C D E F G
A B C D E F G
a b c d e f g
a b c d e f g
will produce the following chromosomes if there is a crossing-over event between the 2nd and 3rd chromosomes from the top:
A B C D E F G
A B c d e f g
a b C D E F G
a b c d e f g
Thus, instead of producing only two types of chromosome (all capital or all lower case), four different chromosomes are produced. This doubles the variability of gamete genotypes. The occurrence of a crossing-over is indicated by a special structure, a
chiasma (plural chiasmata) since the recombined inner alleles will align more with others of the same type (e.g. a with a, B with B). Near the end of Prophase I, the homologous chromosomes begin to separate slightly, although they remain attached at chiasmata.
Crossing-over between homologous chromosomes produces chromosomes with new associations of genes and alleles. Image from Purves et al., Life: The Science of Biology, 4th Edition, by Sinauer Associates (
www.sinauer.com) and WH Freeman (
www.whfreeman.com), used with permission.
Events of Prophase I (save for synapsis and crossing over) are similar to those in Prophase of mitosis: chromatin condenses into chromosomes, the
nucleolus dissolves, nuclear membrane is disassembled, and the
spindle apparatus forms.
Major events in Prophase I. Image from Purves et al., Life: The Science of Biology, 4th Edition, by Sinauer Associates (
www.sinauer.com) and WH Freeman (
www.whfreeman.com), used with permission.
Metaphase I
Back to TopMetaphase I is when tetrads line-up along the equator of the spindle. Spindle fibers attach to the centromere region of each homologous chromosome pair. Other metaphase events as in mitosis.
Anaphase I
Back to TopAnaphase I is when the tetrads separate, and are drawn to opposite poles by the spindle fibers. The centromeres in Anaphase I remain intact.
Events in prophase and metaphse I. Image from Purves et al., Life: The Science of Biology, 4th Edition, by Sinauer Associates (
www.sinauer.com) and WH Freeman (
www.whfreeman.com), used with permission.
Telophase I
Back to TopTelophase I is similar to Telophase of mitosis, except that only one set of (replicated) chromosomes is in each "cell". Depending on species, new nuclear envelopes may or may not form. Some animal cells may have division of the centrioles during this phase.
The events of Telophase I. Image from Purves et al., Life: The Science of Biology, 4th Edition, by Sinauer Associates (
www.sinauer.com) and WH Freeman (
www.whfreeman.com), used with permission.
Prophase II
Back to TopDuring Prophase II, nuclear envelopes (if they formed during Telophase I) dissolve, and spindle fibers reform. All else is as in Prophase of mitosis. Indeed Meiosis II is very similar to mitosis.
The events of Prophase II. Image from Purves et al., Life: The Science of Biology, 4th Edition, by Sinauer Associates (
www.sinauer.com) and WH Freeman (
www.whfreeman.com), used with permission.
Metaphase II
Back to TopMetaphase II is similar to mitosis, with spindles moving chromosomes into equatorial area and attaching to the opposite sides of the centromeres in the kinetochore region.
Anaphase II
Back to TopDuring Anaphase II, the centromeres split and the former chromatids (now chromosomes) are segregated into opposite sides of the cell.
The events of Metaphase II and Anaphase II. Image from Purves et al., Life: The Science of Biology, 4th Edition, by Sinauer Associates (
www.sinauer.com) and WH Freeman (
www.whfreeman.com), used with permission.
Telophase II
Back to TopTelophase II is identical to Telophase of mitosis. Cytokinesis separates the cells.
The events of Telophase II. Image from Purves et al., Life: The Science of Biology, 4th Edition, by Sinauer Associates (
www.sinauer.com) and WH Freeman (
www.whfreeman.com), used with permission.
Comparison of Mitosis and Meiosis
Back to TopMitosis maintains ploidy level, while meiosis reduces it. Meiosis may be considered a reduction phase followed by a slightly altered mitosis. Meiosis occurs in a relative few cells of a multicellular organism, while mitosis is more common.
Comparison of the events in Mitosis and Meiosis. Images from Purves et al., Life: The Science of Biology, 4th Edition, by Sinauer Associates (
www.sinauer.com) and WH Freeman (
www.whfreeman.com), used with permission.
Gametogenesis
Back to TopGametogenesis is the process of forming gametes (by definition haploid, n) from diploid cells of the germ line.
Spermatogenesis is the process of forming
sperm cells by meiosis (in animals, by mitosis in plants) in specialized organs known as
gonads (in males these are termed
testes). After division the cells undergo differentiation to become sperm cells.
Oogenesis is the process of forming an
ovum (egg) by meiosis (in animals, by mitosis in the gametophyte in plants) in specialized gonads known as
ovaries. Whereas in spermatogenesis all 4 meiotic products develop into gametes, oogenesis places most of the cytoplasm into the large egg. The other cells, the polar bodies, do not develop. This all the cytoplasm and organelles go into the egg. Human males produce 200,000,000 sperm per day, while the female produces one egg (usually) each
menstrual cycle.
Gametogenesis. Images from Purves et al., Life: The Science of Biology, 4th Edition, by Sinauer Associates (
www.sinauer.com) and WH Freeman (
www.whfreeman.com), used with permission.
Spermatogenesis
Sperm production begins at puberty at continues throughout life, with several hundred million sperm being produced each day. Once sperm form they move into the
epididymis, where they mature and are stored.
Human Sperm (SEM x5,785). This image is copyright Dennis Kunkel at
www.DennisKunkel.com, used with permission.
Oogenesis
The ovary contains many
follicles composed of a developing egg surrounded by an outer layer of follicle cells. Each egg begins
oogenesis as a primary
oocyte. At birth each female carries a lifetime supply of developing oocytes, each of which is in Prophase I. A developing egg (secondary oocyte) is released each month from puberty until menopause, a total of 400-500 eggs.
Oogenesis. The above image is from
http://www.grad.ttuhsc.edu/courses/histo/notes/female.html.
Links
Back to TopAccess Excellence page on MitosisCell Division and the Cell Cycle (University of Alberta): Similar to this page, but with its own glossary and questions.
Amoeba Proteus Mitosis Small photomicrographs of protistan mitosis.
Animated Meiosis Yale University, a simplified series of cartoons about meiosis.
Meiosis Tutorial North Carolina State University, animations and 3-D graphics.
McGill University Mitosis Page Quality site, with photos and downloadable animation and video.
Virtual Meiosis University of Cincinnati, Animated GIF and text/images to explain meiosis.
Definition
The first of the two consecutive divisions of the
nucleus of
eukaryotic cell during
meiosis composed of the following stages:
prophase I,
metaphase I,
anaphase I, and
telophase Scholarship applications for
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Consultative Group on International Agricultural Research
From Wikipedia, the free encyclopedia
Jump to:
navigation,
searchThe Consultative Group on International Agricultural Research (CGIAR) was originally created at the initiative of the
Rockefeller Foundation, which had sponsored international meetings of agronomists at its Bellagio Conference Center in
Lake Como, Italy, from 1968 onwards.
In 1970, foundation officials proposed a worldwide network of agricultural research centers under a permanent secretariat. This was further supported and developed by the
World Bank; on May 19, 1971, with the
FAO,
IFAD and
UNDP as co-sponsors, the CGIAR was established. By 1983 there were thirteen research centers around the world under its umbrella.
[1] CGIAR now has 64 governmental and nongovernmental members and 15 research centres.
At the time of its establishment there was widespread concern that developing countries would succumb to
famine; the successes of the
Green Revolution had started in
Asia and the
Pearson Commission on International Development had urged that the international community undertake "intensive international effort" to support "research specializing in food supplies and tropical agriculture". CGIAR was formed for the coordination of international agricultural research with the goals of poverty reduction and achieving
food security in developing countries through agricultural research.
Active CGIAR Centres
Headquarters location
International Center for Tropical Agriculture (CIAT)
Cali,
ColombiaCenter for International Forestry Research (CIFOR)
Bogor,
IndonesiaInternational Maize and Wheat Improvement Center (CIMMYT)
El Batán,
Mexico State,
MexicoInternational Potato Center (CIP)
Lima,
PeruInternational Center for Agricultural Research in the Dry Areas (ICARDA)
Aleppo,
SyriaWorldFish Center (International Center for Living Aquatic Resources Management, ICLARM)
Penang,
MalaysiaWorld Agroforestry Centre (International Centre for Research in Agroforestry, ICRAF)
Nairobi,
KenyaInternational Crops Research Institute for the Semi-Arid Tropics (ICRISAT)
Hyderabad,
IndiaInternational Food Policy Research Institute (IFPRI)
Washington, D.C.,
United StatesInternational Water Management Institute (IWMI)
Battaramulla,
Sri LankaInternational Institute of Tropical Agriculture (IITA)
Ibadan,
NigeriaInternational Livestock Research Institute (ILRI)
Nairobi,
KenyaBioversity InternationalMaccarese,
Rome,
ItalyInternational Rice Research Institute (IRRI)
Los Baños, Laguna,
PhilippinesAfrica Rice Center (West Africa Rice Development Association, WARDA)
Bouaké,
Côte d'Ivoire /
Cotonou,
BeninDefunct CGIAR Centres
Headquarters
Change
International Livestock Centre for Africa (ILCA)
Addis Ababa,
Ethiopia1994: merged with ILRAD to become ILRI
International Laboratory for Research on Animal Diseases (ILRAD)
Nairobi,
Kenya1994: merged with ILCA to become ILRI
International Network for the Improvement of Banana and Plantain (INIBAP)
Montpellier,
France1994: became a programme of Bioversity International
International Service for National Agricultural Research (ISNAR)
The Hague,
Netherlands2004: dissolved, main programmes moved to IFPRI
CGIAR also organises a number of inter-Center initiatives and Systemwide Programmes (SP), and Challenge Programmes (CP). The Initiatives and SPs cover cross-Center issues. The CPs are time-bound, independently-governed programs of high-impact research, executed in a partnership among a wide range of institutions. Currently there are three in operation: the Generation Challenge Programme, Harvest Plus and Water and Food.
[
edit] Notes
^ Establishment of CGIAR - see Mark Dowie, American Foundations: An Investigative History, Cambridge, Massachusetts: MIT Press, 2001, (p.114)
[
edit] External links
Official websiteGeneration Challenge ProgrammeHarvestPlus Challenge ProgrammeCGIAR Challenge Program on Water and FoodInstitutional Learning and Change (ILAC)Central Advisory Service on Intellectual PropertyICT-KM: the CGIAR program on ICT and Knowledge ManagementCGIAR Systemwide Program on Collective Action and Property Rights (CAPRi)[
hide]
v •
d •
eConsultative Group on International Agricultural Research (CGIAR) Centers
International Center for Tropical Agriculture (CIAT) ·
Center for International Forestry Research (CIFOR) ·
International Maize and Wheat Improvement Center (CIMMYT) ·
International Potato Center (CIP) ·
International Center for Agricultural Research in the Dry Areas (ICARDA) ·
International Center for Living Aquatic Resources Management (ICLARM) ·
International Centre for Research in Agroforestry (ICRAF) ·
International Crops Research Institute for the Semi-Arid Tropics (ICRISAT) ·
International Food Policy Research Institute (IFPRI) ·
International Water Management Institute (IWMI) ·
International Institute of Tropical Agriculture (IITA) ·
International Livestock Research Institute (ILRI) ·
Bioversity International ·
International Rice Research Institute (IRRI) ·
West Africa Rice Development Association (WARDA)Retrieved from "
http://en.wikipedia.org/wiki/Consultative_Group_on_International_Agricultural_Research"
Categories:
Agriculture organizations Rockefeller Foundation World Bank Agricultural research institutesViews
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